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The ECG Blog with Reid

Cardiac Action Potentials: From Depolarization to Myocardial Contraction May 12, 2025

While cardiac action potentials are often reduced to textbook waveforms and phases, their ultimate purpose is mechanical: to produce calcium influx that activates myocardial contraction. Every depolarization on an ECG—every P wave, QRS complex, and T wave—represents a deeper cellular orchestration o...

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